Reviews, Citations, Testimonials
Reviews
Vigene aims for excellence in the viral vector and plasmid products and services we offer to our customers. We pride ourselves on our high customer return rate and frequently ask our customers to provide feedback on our products and services.
24 Ratings | Based on our customer feedback surveys
Citations
Below is a selection of recent publications and testimonials from scientists that have used our products and services.
AAV
Li, H. et al. Brg1 promotes liver fibrosis via activation of hepatic stellate cells. Experimental Cell Research. 364, 191–197 (2018). DOI: 10.1016/j.yexcr.2018.02.003
Hu, J. et at. Comparative study on infection rate of different adeno-associated virus for knee joint cartilage in mice. Zhongguo Gu Shang. 32, 750-755 (2019) DOI: 10.3969/j.issn.1003-0034.2019.08.015
Osborne, A. et al. Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin-related kinase receptor-B signaling. Cell Death & Disease. 9, 1007 (2018). DOI: 10.1038/s41419-018-1041-8
Pomeroy, E. J. et a. A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy. Molecular Therapy. 28, 52-63, (2020). DOI: 10.1016/j.ymthe.2019.10.009
Rogers, G. L. Homologous Recombination-Based Genome Editing by Clade F AAVs Is Inefficient in the Absence of a Targeted DNA Break. Molecular Therapy. 27, 1729-1736, (2019) DOI: 10.1016/j.ymthe.2019.08.019
Schober, A. L. et al. Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo. Frontiers in Cellular Neuroscience. 10, 262 (2016). DOI: 10.3389/fncel.2016.00262
Shin, H. et al. A Crucial Role of ACBD3 Required for Coxsackievirus Infection in Animal Model Developed by AAV-Mediated CRISPR Genome Editing Technique. Viruses. 13, 237 (2021). DOI: 10.3390/v13020237
Sommer, C. et al. Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma. Molecular Therapy. 27, 1126-1138 (2019) DOI: 10.1016/j.ymthe.2019.04.001
Tang, X. et a. Neurotoxicity of HIV-1 Tat is attributed to its penetrating property. Scientific Reports. 10, 14002 (2020). DOI:
10.1038/s41598-020-70950-x
Yang, J. et al. Coupling optogenetic stimulation with NanoLuc-based luminescence (BRET) Ca++ sensing. Nature Communications 7, 13268 (2016). DOI: 10.1038/ncomms13268
Yin, C. et al. In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models. Molecular Therapy. 25, 1168–1186 (2017). DOI: 10.1016/j.ymthe.2017.03.012
Zakas, P. M. et al. Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction. Nature Biotechnology. 35, 35–37 (2017). DOI: 10.1038/nbt.3677
Zeng, J. et al. Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice. Arthritis Research & Therapy. 21, 205 (2019). DOI: 10.1186/s13075-019-1985-9
Zhao, X. et al. Caspase-2 cleavage of tau reversibly impairs memory. Nature Medicine. 22, 1268–1276 (2016). DOI: 10.1038/nm.4199
Zingg, B. et al. AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors. Neuron 93, 33–47 (2017). DOI:10.1016/j.neuron.2016.11.045
Adenovirus
Li, H. et al. p38 MAPKMK2 pathway regulates the heat stress-induced accumulation of reactive oxygen species that mediates apoptotic cell death in glial cells. Oncology Letters 15, 775–782 (2018). DOI: 10.3892/ol.2017.7360
Liu, L. et al. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front. Molecular Neuroscience 11, (2018). DOI: 10.3389/fnmol.2018.00076
Song, X. et al. Temozolomide–perillyl alcohol conjugate downregulates O 6 -methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer. Cell Death & Disease 9, 202 (2018). DOI: 10.1038/s41419-017-0193-2
Sun, J.-X. et al. SNAI1, an endothelial–mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization. Angiogenesis 1–18 (2018). DOI: 10.1007/s10456-018-9614-9
Zhang, L. et al. Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway. International Journal of Molecular Medicine. 41, 1293–1304 (2018). DOI: 10.3892/ijmm.2017.3327
Zeng, J. et al. Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice. Arthritis Research & Therapy. 205, 19 (2019). DOI: 10.1186/s13075-019-1985-9
Zhou, W. et al. PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research 37, 215 (2018). DOI: 10.1186/s13046-018-0890-4
Lentivirus
Goffena, J. et al. Elongator and codon bias regulate protein levels in mammalian peripheral neurons. Nature Communications 9, 889 (2018). DOI: 10.1038/s41467-018-03221-z
Li, Y. et al. MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells. BMC Cancer 18, 404 (2018). DOI: 10.1186/s12885-018-4233-9
Meng, D. et al. MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells. Onco Targets Ther 11, 7733–7743 (2018). DOI: 10.2147/OTT.S187221
Mostofa, A., Punganuru, S. R., Madala, H. R. & Srivenugopal, K. S. S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells. Neoplasia 20, 305–323 (2018). DOI: 10.1016/j.neo.2018.01.010
Sun, S. et al. Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming. Cell Death & Disease 8, e2870 (2017). DOI: 10.1038/cddis.2017.273
Xie, H. et al. MEIS-1 level in unresectable hepatocellular carcinoma can predict the post-treatment outcomes of radiofrequency ablation. Oncotarget 9, 15252–15265 (2018). DOI: 10.18632/oncotarget.24165
Plasmid
Bao, X. et al. Capturing the interactome of newly transcribed RNA. Nature Methods 15, 213–220 (2018). DOI: 10.1038/nmeth.4595
Chen, Z., Jiang, Z., Zhang, W. & He, B. Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib. Cancer Manag Res 10, 3057–3067 (2018). DOI: 10.2147/CMAR.S167781
Chung, I.-C. et al. Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis. Sci Rep 6, 36214 (2016). DOI: 10.1038/srep36214
Gong, Z. et al. Genome wide identification of long noncoding RNAs in CCl4 induced liver fibrosis via RNA sequencing. Molecular Medicine Reports 18, 299–307 (2018). DOI: 10.3892/mmr.2018.8986
Liu, F. et al. Cleavage of potassium channel Kv2.1 by BACE2 reduces neuronal apoptosis. Molecular Psychiatry 1 (2018). DOI: 10.1038/s41380-018-0060-2
Luo, J. et al. HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3. Cancer Sci. 109, 317–329 (2018). DOI: 10.1111/cas.13453
Hu, H. et al. Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3. Molecular Cancer 17, 18 (2018). DOI: 10.1186/s12943-018-0761-9
Tao, L. et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature 538, 350–355 (2016). DOI: 10.1038/nature19799
Ying, T.-H. et al. Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells. Sci Rep 6, 29385 (2016). DOI: 10.1038/srep29385
Zhang, J. et al. Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice. Sci Rep 6, (2016). DOI: 10.1038/srep33856
Testimonials
“The customer service has been really good. They always manage to go above and beyond and they take our needs seriously.”
Samantha Chin Research Associate at Casebia Therapeutics
"Great customer service and great products"
Miranda Williams Associate Scientist at ElevateBio
"I'm a consultant for a start-up gene therapy company and have generally been very pleased with the interactions with Vigene"
Janice Phillips Principal at JAPhillips Consulting, LLC
"Keep up the great work!"
Brent French Professor of Biomedical Engineering at University of Virginia
Review Details
5 Star Product Review
AAV Controls
AAV Controls
AAV Controls
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
GMP Service (Viral Vector or Plasmid)
Lentivirus Custom Production
Lentivirus Custom Production
Lentivirus Custom Production
4 Star Product Reviews
AAV Controls
AAV Controls
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
AAV Custom Production
Plasmid Custom Production
3 Star Product Reviews
AAV Custom Production
2 Star Product Reviews
AAV Custom Production
1 Star Product Reviews